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101.
推进信息化和工业化融合(简称“两化融合”)是我国长期坚持的战略部署,也是协同推进“制造强国”和“网络强国”建设的重要抓手。过去十年,两化融合在推动我国企业提质增效、行业转型升级、促进区域协调发展等方面取得一系列重要进展,有力支撑了我国经济高质量发展。分析全国31个省市、100余个细分行业、15万余家企业的两化融合评估数据发现,我国两化融合发展已经实现由“金字塔型”到“纺锤型”结构性升级,区域两化融合差距持续收窄并呈现“西快东稳”态势,重点行业纵向管控集成与横向产供销集成均实现突破性进展,不同类型企业间发展水平不平衡呈缩小态势,数字化管理、智能化生产、网络化协同、个性化定制、服务化延伸等新模式蓬勃发展带来企业业务效率大幅改善,以及经济效益和社会效益“双丰收”。 相似文献
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INTRODUCTION Nitrogen oxides (NOx) are significant airborne contaminants resulting from fossil fuels combustion. The use of metal chelate additives for combined re- moval of NOx and SO2 in FGD (flue-gas desulfuriza- tion) systems was investigated by several groups (Harriott et al., 1993; Tsai et al., 1989; Shi et al., 1996a; 1997). Fe(II)EDTA (EDTA, ethylenediami- netetraacetate) as an additive for removing nitric oxide (NO) from flue gas had been extensively stud- ied, with the … 相似文献
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Hanumanthappa Nandeesha Medha Rajappa Tamilarasu Kadhiravan Krishnamoorthy Srilatha Kottyen Thazhath Harichandrakumar Durgadevi Thyagarajan 《Indian journal of clinical biochemistry : IJCB》2016,31(1):117-120
The severity of alcoholic cirrhosis depends on the presence of liver inflammation and fibrogenesis. Previous studies have hypothesized that carbohydrate deficient transferrin can be used as marker of liver impairment in alcoholic liver disease patients. The present study was designed to assess whether carbohydrate deficient transferrin is associated with procollagen III peptide and predict fibrosis in alcohol cirrhosis patients. We enrolled 48 patients with alcoholic cirrhosis and 38 healthy controls. Serum carbohydrate deficient transferrin, procollagen III peptide and interleukin-6 levels were estimated in both groups. Serum carbohydrate deficient transferrin, procollagen III peptide and interleukin-6 were significantly increased in alcoholic cirrhosis patients compared to controls. Stepwise regression analysis showed that carbohydrate deficient transferrin (adjusted R2 = 0.313, β = 0.362, p = 0.003) and interleukin-6 (adjusted R2 = 0.194, β = 0.459, p = 0.001) were positively associated with procollagen III peptide when age, duration and amount of alcohol consumption were considered as covariates. We conclude that elevated carbohydrate deficient transferrin and interleukin-6 act as predictors of fibrosis in alcoholic cirrhosis. 相似文献
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随着我国逐渐进入老龄化社会,失语症患者逐年增加,目前关于失语症的研究主要集中在认知神经科学领域,而现阶段研究相对较少的失语症的语言学研究更有助于加深对失语症本质的认识。该文基于Citespace的可视化分析,对失语症近年的发文量、失语症的研究方向以及失语症的语言学研究进行分析,进一步探讨了失语症的研究现状。 相似文献
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[摘要]：文章利用当前最著名的可视化分析软件Citespace II对从SCI与SSCI中下载的1988—2010年间信息开放获取研究的全部文献做了详细的量化可视分析,绘制了信息开放获取研究文献的共引网络图谱,分析了关键节点文献,探讨了信息开放获取研究的知识基础,揭示了其研究热点的变化情况以及信息开放获取运动在有关国家与研究机构的开展情况。 相似文献
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Jon Baggaley 《Distance Education》2014,35(1):133-140
The statement by Hunter R. Rawlings III that “there are no good studies on what constitutes bad online pedagogy” coincides with the creation of a Global Learning Council to define the guidelines that previous online educators have allegedly failed to identify. This article discusses these disparaging remarks by the President of the Association of American Universities about the distance education (DE) field and the likely influence on the Council’s deliberations by the motives of its members—American university presidents, corporate representatives, and providers of support for massive open online courses. The influence of their conclusions on public attitudes to new educational practices is anticipated, and the distorted pedagogical principles being offered in support of massive course practices are defined as arising from a form of plagiarism. A formal response by DE and online learning specialists to the rejection of their previous literature is encouraged; and an analysis of the situation is offered by a fictitious educational historian in the year 2031. 相似文献
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Aditi Gupta Gora Dadheech Dharamveer Yadav Praveen Sharma Shiv Gautam 《Indian journal of clinical biochemistry : IJCB》2014,29(2):196-201
Schizophrenia is a psychotic disorder with a complex pathophysiology and requires treatment that includes long term administration of antipsychotics that is said to be associated with metabolic syndrome. This study was designed to evaluate the impact of seven different antipsychotics prescribed to schizophrenic patients, on development of metabolic syndrome in the patients. A total of 210 patients with schizophrenia (30 patients in each drug therapy group) were recruited according to ICD-10 criteria and were assigned to receive the drug for 16 weeks. Measurement of anthropometric (body weight, waist circumference, blood pressure) and biochemical parameters (glucose, insulin, HOMA-IR, triglycerides, LDL, HDL) was done and the patients were subjected to ATP-III defined criteria for metabolic syndrome. Patients undergoing treatment with olanzapine were more prone to metabolic syndrome as the drug induces weight gain after 16 weeks of treatment. It also induces dyslipidemia (P < 0.001) and hyperglycemia (P < 0.01). Clozapine was found to be second most potent drug in inducing metabolic syndrome as the weight in clozapine treated patients increased after 16 weeks, along with a significant increase in glycemic (P < 0.001) and lipid parameters (P < 0.01). Aripriazole and amisulphride are comparatively safer drugs as their role in inducing metabolic abnormalities in schizophrenic patients was insignificant, although the impact of long term administration of these drugs needs to be explored. It is clear from the study that antipsychotic treatment induces metabolic syndrome so, it becomes important that the metabolic and cardiovascular risk factors should be surveillance regularly in schizophrenic patients undergoing antipsychotic treatment. 相似文献
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摘要：目的：观察膳食补充亮氨酸对增龄小鼠骨骼肌蛋白质合成的影响并初步探讨其可能性机制。方法：13月龄雄性ICR小鼠据体重随机分为补充亮氨酸、补充丙氨酸以及空白对照组,补充亮氨酸和补充丙氨酸组分别在饲料中给予亮氨酸（5%）和丙氨酸（3.4%）添加8周,空白对照组则进食普通维持饲料。末次给食后禁食17 h并处死小鼠,用血糖仪检测血糖;ELISA检测血清胰岛素;HE染色观察腓肠白肌肌纤维适应性变化;Western blotting检测PI3K III（mVPS34）与MHCⅡ蛋白表达及mTOR、p70S6K、4E-BP1磷酸化率。结果：添加亮氨酸并未显著影响小鼠体重与采食量,且未致胰岛素与血糖水平变化不显著。腓肠白肌湿重、湿重/体重比值、肌纤维横截面积与直径表现出增大的趋势,但变化并不显著。但肌肉蛋白总量、mVPS34与MHCⅡ的蛋白表达及mTOR、p70S6K、4E-BP1磷酸化率均显著增加。结论：5%比例亮氨酸具有促进骨骼肌蛋白质合成并减缓老年前期小鼠肌肉的萎缩的潜力,其机制可能涉及肌细胞内PI3K III（mVPS34）/ mTOR/ p70S6K信号通路的活化。 相似文献
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以ISI Web of Science收录的以“information management”为主题的文献作为研究对象,利用CiteSpaceⅡ工具,对信息管理研究文献进行可视化研究,包括时间分布、地区分布、作者机构分布、期刊分布、学科分布、学科代表人物及其作品,展现信息管理的研究热点和研究前沿,揭示信息管理研究的现状,为我国信息管理的发展提供参考. 相似文献